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In a randomised, placebo-controlled double blinded phase 1 study of ascending single doses in healthy overweight humans, cotadutide was shown to be safe and, in common with the GLP-1 analogues, to be associated with dose-dependent gastrointestinal adverse events especially nausea and vomiting

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Heres how GLP-1 therapy can be a strategic tool for patients with Hashimotos when used correctly and under medical guidance

The expression of the protein associated with the ZO-1 junction prevents the increase of pressure in the abdominal cavity, which eliminates the occurrence of leaky gut syndrome, a very important aspect in the postoperative state